Stem cell therapy for autoimmune diseases involves the use of stem cells to modulate the immune system and potentially restore its normal function.
The specific approach can vary depending on the type of autoimmune disease being targeted, but there are three main types of stem cell transplant treatments used:
1) Hematopoietic Stem Cell (HSCT):
2) Mesenchymal Stem Cell (MSC):
3) Induced Pluripotent Stem Cells (iPSC):
Stem cell treatments for autoimmune diseases are an area of active research and clinical investigation. Autoimmune diseases occur when the body’s immune system mistakenly attacks its own healthy cells and tissues, leading to inflammation and damage. Traditional treatments for autoimmune diseases typically involve immune-suppressing medications that aim to control the immune response.
Stem cell therapy for autoimmune diseases involves the use of stem cells to modulate the immune system and potentially restore its normal function. The specific approach can vary depending on the type of autoimmune disease being targeted, but there are two main types of stem cell treatments used:
a) Hematopoietic Stem Cell Transplantation (HSCT): This procedure involves the transplantation of hematopoietic stem cells, which are responsible for generating various blood cells, including immune cells. Prior to the transplant, the patient’s immune system is typically suppressed or depleted using chemotherapy or radiation. Then, the patient receives a transplant of their own stem cells or those from a compatible donor. The goal is to “reboot” the immune system and promote the development of a new immune system that no longer attacks the body’s tissues.
b) Mesenchymal Stem Cell (MSC) Therapy: Mesenchymal stem cells are a type of adult stem cell found in various tissues, such as bone marrow, adipose tissue (fat), and umbilical cord tissue. These cells have immunomodulatory properties, meaning they can regulate the immune response and reduce inflammation. MSCs can be isolated, expanded in the laboratory, and then infused into the patient. They can exert their effects by suppressing the activity of the immune system and promoting tissue repair and regeneration.