Laboratory research, cellular processing and translational applications
EspañolThe CELLMEX laboratory section is focused on the biological platforms presently associated with our treatment programmes, together with current in-vitro and ex-vivo research intended to improve cellular understanding, process control and translational use.
Our laboratory work is centred on cellular and cell-derived biological platforms relevant to the regenerative medicine services being developed and offered through CELLMEX.
The present programme includes laboratory handling of mesenchymal stromal-cell cultures, observation of cellular behaviour under controlled in-vitro conditions, preparation of cell-conditioned materials and preservation of selected laboratory samples.
Ex-vivo work is performed outside the patient using biological material or cultured cells before any subsequent clinical decision or application is considered.
Laboratory activity and clinical care are related but distinct. Clinical treatment decisions remain the responsibility of qualified physicians and require patient-specific medical assessment.
The activities below reflect the laboratory areas presently relevant to our treatment and research programmes.
Laboratory culture of MSC populations under controlled conditions supports cellular expansion, observation and preparation for defined research or clinical-development purposes.
Cell-conditioned media may contain soluble proteins, growth factors, cytokines, metabolites and extracellular particles released during culture.
In-vitro studies are conducted outside a living organism using cultured cells, culture media or isolated biological components.
Ex-vivo work involves cells or biological material obtained from a donor or patient and studied or processed outside the body under controlled laboratory conditions.
The exact biological product, preparation and route of administration must be determined for each patient by the treating medical team.
Laboratory activities may support the preparation, handling and documentation of mesenchymal stromal-cell products considered for selected regenerative or immunomodulatory applications.
Research and preparation may include conditioned media, secretome-associated materials and selected extracellular-vesicle fractions, subject to product-specific characterisation.
Laboratory-supported regenerative approaches may be evaluated for selected musculoskeletal, tissue-repair and inflammatory clinical settings.
Selected cell-derived or cell-free preparations may be evaluated for local dermal, scalp or tissue-quality applications under physician supervision.
Current work includes examination of biological platforms associated with inflammatory signalling and immune-system interaction.
Research may explore controlled culture conditions intended to influence MSC phenotype or tissue-associated differentiation in vitro.
Current research is intended to improve biological understanding and laboratory control. Research findings do not automatically establish clinical efficacy.
Evaluation of how cell source, passage, medium, density, time and environmental conditions may influence cell growth and observable phenotype.
Examination of cell-derived soluble and vesicular components associated with MSC-conditioned culture systems.
Assessment of handling, concentration, storage and cryogenic-preservation variables relevant to cell and sample integrity.
In-vitro investigation of controlled differentiation or lineage-associated characteristics, including the need to confirm phenotype and function before any translational claim is made.
Biological materials, culture supplies or samples are received and identified for the intended work.
Work is performed using appropriate aseptic handling and defined laboratory procedures.
Cells or cell-derived materials are cultured, collected, separated or prepared according to the relevant laboratory objective.
Relevant process information and observable findings are recorded for review.
Materials are stored, preserved or transferred for the next authorised laboratory or clinical step.
The photographs below document laboratory personnel, cell-culture vessels, a protected work area, cryogenic-storage vessels and microscopy-related workspace.
Laboratory staff member handling stacked multi-layer culture vessels while wearing protective clothing.
Enclosed and illuminated laboratory workspace used for controlled handling of materials.
Laboratory cryogenic-storage vessel used for preservation of selected cells or samples.
Laboratory workspace containing microscopy equipment, computer support and cryogenic storage vessels.
In-vitro and ex-vivo results describe biological behaviour under defined laboratory conditions. They do not automatically predict safety or benefit in patients.
Any clinical application must consider the precise product identity, manufacturing process, dose, route of administration, patient condition, supporting evidence and applicable regulatory requirements.
CELLMEX treatment decisions should therefore remain physician-led and based on individual medical review, informed consent and appropriate follow-up.
Learn more about MSC therapy, extracellular vesicles, exosomes, secretome, conditioned media and other CELLMEX development platforms.